Oh, no that is just the 4.5.2 patch, for those who has already downloaded the 4.5.0 (that was needed to install AFTER they actually installed the official NESmaker 4.5.0).
For official releases, always check here: https://www.thenew8bitheroes.com
So... just get the NESmaker 4.5 zip file from the official site (download). it will contain already all the patches so far. Unzip it, then you can run NESmaker by following the tutorials from the official site https://www.thenew8bitheroes.com/learn
Keep it mind, you can't use NESmaker without following those tutorials... this version is a beta version, meant to be used for those tutorials (the Summer Camp series)